Topic 2: Towards diverse, sustainable and circular food processing systems
We bring strong expertise in gene expression, epigenetics, and the molecular effects of Mediterranean bioactive compounds. Our contribution to FutureFoodS focuses on two high-impact innovations: (1) nutrigenomic validation of senolytic compounds derived from pseudocereal by-products, and (2) the development of plant-derived extracellular vesicles as fully natural delivery systems to enhance bioavailability. My laboratory has demonstrated how dietary bioactives modulate DNA methylation, activate autophagy, and protect against cellular damage, and we are equipped to perform transcriptomic and epigenomic profiling of valorized ingredients. We also have the infrastructure to isolate and optimize extracellular vesicles taken directly from agricultural side-streams, enabling a zero-waste approach. These vesicles protect senolytic molecules through digestion, enhance intestinal uptake, and carry their own regulatory microRNAs. I propose leading work packages on molecular validation and vesicle-based delivery, generating evidence essential for regulatory approval and functional food development. My expertise integrates seamlessly with consortium partners, supporting scalable processing, advanced analytics, and AI-enabled personalized nutrition.
The Department of Environmental Engineering, known as STEBICE, focuses on the study and research of environmental issues and sustainable practices. It offers interdisciplinary programs that integrate engineering, science, and policy to address challenges such as pollution, resource management, and climate change. STEBICE emphasizes practical solutions and collaborates with various industries and governmental bodies, preparing students for impactful careers in environmental protection and management. The department also engages in cutting-edge research, contributing to both local and global sustainability efforts.